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Timothy L. Vollmer, MD
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Brian R. Apatoff, MD, PhD
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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
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Saturday

 

Comparative effectiveness of Copaxone (glatiramer acetate) and interferon beta formulations in relapsing–remitting multiple sclerosis: STUDY

 

Latest Comments From Subject Time Posted

Latest Comments
From Subject Time Posted
1 NEW! » Jeannine Elan Extends Tysabri's Reach to Canada Oct 8 2006 07:46
1 NEW! » Jeannine 10 Top Australian Scientists Predict Major Medical Advances in MS (download free report) Oct 10 2006 13:11
1 NEW! » Jeannine NEUROVAX: PRESS RELEASE FROM IMMUNE RESPONSE CORP. Oct 10 2006 13:06
1 NEW! » "Gamma Julie" Should Job Hunters Reveal Chronic Illness? The Pros and Cons..[update] Oct 31 2006 03:41
1 NEW! » Jeannine HUMAN STEM CELLS DELAY START OF LOU GEHRIG'S DISEASE IN RATS Oct 15 2006 10:02
1 NEW! » Jeannine Tysabri and Avonex add customer service reps Oct 17 2006 07:34
1 NEW! » Jeannine "Take 10 laps and call me in the morning" Oct 17 2006 09:15
1 NEW! » Jeannine "inmate moved to hospital" (AN UPDATE OF LAST WEEKS STORY: "INMATE WITH MS" Oct 17 2006 09:42
1 NEW! » Jeannine Fampridine SR - NEW DRUG IN PIPELINE Oct 18 2006 09:42
1 NEW! » Jeannine [PROFESSIONAL ABSTRACT] Oct 18 2006 09:43
1 NEW! » David "Copaxone allows some MS patients to retain mobility" Oct 19 2006 19:50
1 NEW! » Lora Future-directed thinking and depression in MS [READ LIZZY'S COMMENT!!!] Oct 28 2006 15:03
1 NEW! » Jeannine MS BIKE TREK Oct 19 2006 09:38
1 NEW! » WaterDragon STEM CELL: "Federal government promotes donation of umbilical cords for stem cell transplants" Oct 20 2006 00:51
1 NEW! » Jeannine Development of an anti-IL-17A auto-vaccine... Oct 20 2006 09:05
1 NEW! » Jeannine GREAT PERSONAL STORY: Oct 20 2006 15:17
1 NEW! » Jeannine "Acute leukaemia in two multiple sclerosis patients treated with mitoxantrone" Oct 20 2006 15:21
1 NEW! » Jeannine The Effect of dose and frequency of interferon beta-1a administration Oct 20 2006 15:31
1 NEW! » Jeannine CDP323: NEW DRUG IN PIPLINE Oct 21 2006 09:58
1 NEW! » Jeannine Did you know that Colorado has one of the highest prevalence rates of MS in the US Oct 21 2006 09:59
1 NEW! » Jeannine Write in Candidate Denise Clement will work for free! Oct 21 2006 10:00
1 NEW! » Jeannine Methylthioadenosine Effective in Animal Models of Multiple Sclerosis Oct 22 2006 07:32
1 NEW! » Jeannine UK: cannabis pill test Oct 22 2006 07:34
1 NEW! » Jeannine Clustering of autoimmune diseases in families with a high-risk for MS: Oct 23 2006 07:36
1 NEW! » Jeannine The female to male sex ratio by year of birth has been increasing for at least 50 years Oct 23 2006 07:39
1 NEW! » Jeannine Photography studio is donating fees to MS Oct 23 2006 08:17
1 NEW! » Jeannine Boston Home's 125th Anniversary - Oct 24 2006 09:28
1 NEW! » Jeannine UK...MP's Back MS Campaign Oct 24 2006 09:32
1 NEW! » Jeannine Dutch prosecutors ask highest court to quash appeals court medicinal cannabis decision Oct 24 2006 09:34
1 NEW! » Jeannine MBP8298 Oct 24 2006 09:35
1 NEW! » deleted account Live HealthTalk - 30 Minutes of Q&A with Nurse Piper [sponsored by a drug company] Oct 24 2006 19:50
1 NEW! » Jeannine High-Dose Cyclophosphamide Study: GOOD RESULTS!!! Oct 25 2006 09:32
1 NEW! » Jeannine NEW DRUG IN PIPELINE: MCT-125 Oct 25 2006 09:35
1 NEW! » Jeannine 3 Guys, 3 Bikes, 7,000 Miles Through South America for MS Oct 25 2006 09:39
1 NEW! » Jeannine 14-year old bicyclist rides for MS Oct 26 2006 08:24
1 NEW! » Jeannine Accelerated Cure Project for MS today announced the formation of their MS Repository Oct 26 2006 08:29
1 NEW! » Jeannine A MSnewsChannel.com Video: A TIP FROM HEATHER ON EASING REBIF PAIN Oct 26 2006 09:02
1 NEW! » Jeannine TYSABRI® GOOD FOR LUPUS TOO...PER THIS PRESS RELEASE FROM ELAN Oct 26 2006 09:04
1 NEW! » Jeannine VISIT OUR "TYSABRI NEWS" WEBSITE Oct 26 2006 09:08
1 NEW! » Jeannine Joseph Eisen suffers from Primary Progressive Multiple Sclerosis....AGENGY HELPS WITH HIS LEGAL Oct 27 2006 08:18
1 NEW! » Jeannine Campus Fudraiser....(good idea for other colleges) Oct 27 2006 14:22
1 NEW! » David WATCH VIDEO: Selling CDs as a MS Fundraiser Oct 29 2006 09:03
1 NEW! » Jeannine If a sibling has MS, you are 15 to 25 times more likely to develop it yourself Oct 29 2006 09:16
1 NEW! » Jeannine UK: NO JAIL FOR HUSBAND WHO HELPED WIFE'S SUICIDE Oct 29 2006 09:18
1 NEW! » Jeannine Car enthusiasts, bikers rally MS Oct 29 2006 09:26
1 NEW! » Jeannine UPDATE ON MS CANDIDATE WHOSE OPPONENT MADE A NASTY WHEELCHAIR COMMENT Oct 30 2006 08:32
2 NEW! » Jeannine "MS NO LONGER A DEATH KNELL FOR PATIENTS" Oct 30 2006 08:43
2 NEW! » David WATCH VIDEO PLUS FREE READ OF CHAPTER 1 : Today show host Meredith Vieira talks with Teri Garr Oct 30 2006 20:27
1 NEW! » WaterDragon "Ed Johns says he feels like a new man" [I WOULDN'T LET MY SON DO THIS!-stan] Oct 31 2006 01:11
1 NEW! » Jeannine TYSABRI.....Biogen Idec Third-Quarter Net Rises Sixfold on MS Drugs Oct 31 2006 09:18
1 NEW! » Jeannine DETROIT FUNDRAISER Nov 1 2006 10:08
1 NEW! » Jeannine ABSTRACT FOR DOCS, NURSES Nov 1 2006 10:09
2 NEW! » Jeannine .....control of their health with exercise, even though it might bring short-term discomfort Nov 1 2006 15:05
1 NEW! » Darth Woky ™ GREAT READ: MS afflicts about twice as many females as males Nov 2 2006 01:15
2 NEW! » David Cladribine used to treat some cancers and possibly MS: Brigham Young University Nov 2 2006 19:15
2 NEW! » David I JUST RECEIVED THIS PRESS RELEASE FROM TEVA RE: COPAXONE {NOT IMPORTANT :-)] Nov 2 2006 19:23
2 NEW! » David VOTE: ANOTHER STEM CELL STORY(I can't decide if I should post stem cell stories or not?? -stan) Nov 2 2006 19:33
3 NEW! » David update: DRUG DELAYED BY FDA FOR A MS CONDITION I'VE NOT HEARD OF -HAVE YOU??? -stan Nov 2 2006 19:36
2 NEW! » David MS Linked to Abnormal Liver Test Results Nov 2 2006 19:46
1 NEW! » Rev. cutthroat carnie TYSABRI BAD NEWS:Since July, only 47 of more than 8,500 patients are using Tysabri... Nov 7 2006 08:13
1 NEW! » Jeannine New York City Chapter MS Society: Help Us Reach Our Fundraising Goal for the MS Bike Tour Nov 1 2006 14:43
1 NEW! » Jeannine BAD NEWS ON UCLA PLAYER WE HAVE BEEN REPORTING ON Nov 2 2006 08:27
1 NEW! » Jeannine !!!...Fampridine-SR: WONDERFUL TRIAL RESULTS ON NEW DRUG Nov 2 2006 08:29
2 NEW! » queen_racewife PRESS RELEASE ON NEW DRUG: MBP8298 [TRIALS ARE VERY GOOD OUT OF THE US!!!] Nov 2 2006 08:35
1 NEW! » Mary and Robert GREAT STORY OF PERSEVERANCE Nov 2 2006 10:40
1 NEW! » Jeannine Study sheds light on myelination Nov 3 2006 07:04
1 NEW! » Jeannine FDA Approvals: Interferon-beta-1b (Betaseron) for Use in Early Multiple Sclerosis Nov 3 2006 18:13
1 NEW! » "Gamma Julie" 'miracle drug' is supposedly no good Nov 4 2006 02:01
2 NEW! » Roseanne ENVIRONMENT CAUSE OF WOMEN'S HIGHER RISK OF MS? Nov 4 2006 09:05
1 NEW! » Jeannine cladrabine Nov 4 2006 14:09
2 NEW! » Jeannine MS Society's 'Shining Star Nov 4 2006 14:30
1 NEW! » Jeannine NEW DRUG IN PIPELINE: MBP8298 Nov 4 2006 14:33
3 NEW! » David UK - EXPERTS believe they have discovered a protein which could help create new MS treatments Nov 4 2006 18:14
1 NEW! » Jeannine WONDERFUL STORY OF PERSEVERANCE IN THIS SUNDAY'S NYC MARATHON Nov 5 2006 12:08
1 NEW! » ~Ãngël~™ NPR AUDIO: Studies have found that a six-month Iyengar yoga program helped people with MS comba Nov 5 2006 17:35
2 NEW! » Jeannine "advances on the horizon..." Nov 6 2006 09:12
1 NEW! » Jeannine GREAT ADVICE FOR CAREGIVERS - stan Nov 6 2006 09:28
2 NEW! » Darth Woky ™ (UPDATE ON THIS STORY IS AB0VE) CHURCHILL DOWNS PERSEVERANCE Nov 7 2006 01:22
2 NEW! » "Gamma Julie" Award given to Scott Johnson, President and Founder of the Myelin Repair Foundation Nov 7 2006 04:46
2 NEW! » queen_racewife INTERESTING IMPLANT STUDY....update Nov 8 2006 03:38
1 NEW! » David (READ THE GREAT COMMENTS) TOVAXIN...NEW MS DRUG IN PIPELINE STARTS DOSING Nov 9 2006 22:56
2 NEW! » Lora GOOD INTERVIEW WITH AUTHOR OF NEW BOOK: ABOUT HER MS Nov 10 2006 13:39
2 NEW! » Mary and Robert Man says tai chi gave him second chance at life. Nov 10 2006 17:20
3 NEW! » Jeannine oral Trimesta (estriol)...A NEW MS DRUG IN THE PIPELINE!!!!! [UPDATE]  Nov 10 2006 18:54
1 NEW! » Jeannine STORY OF 37-YEAR OLDS PERSEVERANCE Nov 10 2006 19:00
1 NEW! » Jeannine NEW BROCHURE: Volunteering for a Clinical Trial: Your Guide to Participating in a Trial Nov 10 2006 19:01
1 NEW! » Jeannine ECCO Shoes Plans to Donates $2 Per Pair of Shoes Sold to MS [good idea for US] Nov 10 2006 19:08
1 NEW! » Jeannine 58% of long-term care claimants are younger than 65 and the top five claims causes are MS, Canc Nov 10 2006 19:09
3 NEW! » Jeannine "Advances on the horizon in treating and curing MS" Nov 10 2006 19:15
1 NEW! » Jeannine A medical marijuana ballot in South Dakota Today Nov 10 2006 19:17
1 NEW! » Jeannine study identifies how treatment can limit impact of T-cells in autoimmune diseases  Nov 10 2006 19:19
1 NEW! » Jeannine MS fundraising luncheon in Ne Jersey Nov 10 2006 19:19
1 NEW! » Jeannine Treatment of neuropsychiatric conditions associated with MS Nov 10 2006 19:21
1 NEW! » Jeannine BREEDERS CUP WIN! McLaughlin on his battle with MS (THE STORY ON THIS FROM LAST WEEK IS BELOW) Nov 10 2006 19:23
1 NEW! » Jeannine PERSEVERANCE: PAT KINSLEY GIVE BACK TO KIDS Nov 10 2006 19:27
1 NEW! » Jeannine GREAT AND IMPORTANT STORY ABOUT DOGS AS HELPERS FOR MS PATIENTS - stan Nov 10 2006 19:28
2 NEW! » Jeannine FDA APPROVAL: BETASERON UPDATE Nov 10 2006 19:30
2 NEW! » Jeannine ELK HUNTING & MS STORY Nov 10 2006 19:32
2 NEW! » Jeannine B12 and MS: UK MS SOCIETY EDITORIAL Nov 10 2006 19:33
3 NEW! » Mary and Robert Help fight multiple sclerosis with me - The Bakersfield Voice Nov 11 2006 02:06
2 NEW! » Mary and Robert {PERSEVERANCE}.....Cheri Piekarski's job is a labor of love Nov 11 2006 13:41
1 NEW! » Jeannine MARY MOLDS' MS DOESN'T STOP HER FROM HELPING OTHERS Nov 12 2006 08:05
3 NEW! » ♥Debbie♥ GOOD WHEELCHAIR NEWS: Battle over Payments Cuts by CMS is being won!!!! Nov 13 2006 08:24
3 NEW! » David "I believe that a person who can't read in our society is more handicapped than I am," Merens s Nov 13 2006 20:35
2 NEW! » Key two-headed snake Nov 13 2006 20:42
2 NEW! » MRSMUSTAINE NEW PATENTS FOR MS MED Nov 14 2006 02:08
1 NEW! » "Gamma Julie" Cannabis Study in news this AM Nov 15 2006 01:39
1 NEW! » "Gamma Julie" memory study Nov 15 2006 01:52
3 NEW! » "Gamma Julie" "Research Highlights" from the New York City Chapter of the National Multiple Sclerosis Society Nov 15 2006 01:59
1 NEW! » "Gamma Julie" GREAT ARTICLE...THINGS ABOUT RICHARD PRYOR & HIS DAUGHTER RAIN THAT HAVE NEVER BEEN TOLD!-stan Nov 15 2006 02:17
1 NEW! » "Gamma Julie" GETTING TOUGH ON MEDICINAL POT SELLERS Nov 15 2006 02:29
1 NEW! » queen_racewife SAMANTHA..PERSEVERANCE AND KINDNESS AT 15 YEARS OLD...."SHE IS MY REAL HERO"-stan Nov 15 2006 17:28
2 NEW! » queen_racewife BNC105: PRESS RELEASE ON THIS NEW DRUG IN PIPLINE Nov 15 2006 17:42
4 NEW! » queen_racewife STEM CELL STORY FROM THE UK Nov 15 2006 17:47
1 NEW! » David "laughing and intractable hiccups can occur early in MS" [study] Nov 16 2006 20:02
4 NEW! » David New Wave Of HOPE- Support Group Aims To Aid MS Patients Nov 17 2006 20:25
2 NEW! » David Amy Clawson: Country music artist Nov 17 2006 20:32
1 NEW! » David TYSABRI: Natalizumab Alters T Cell Ratio in MS Patients (Reuters Health) Nov 19 2006 10:09
2 NEW! » Alpha [GREAT READ] Geographical disparity of Diseases Nov 19 2006 18:55
1 NEW! » Jenn MBP8298: NEW DRUG IN PIPELINE Nov 19 2006 20:13
4 NEW! » Jenn ANOTHER CRAZY STORY FROM THE UK: "FREEZE TREATMENT FOR MS" Nov 19 2006 20:24
1 NEW! » Tim Foolery There are a lot of new things in Krystal Hexamer's life: Research Promises New Treatment for MS Nov 20 2006 07:38
4 NEW! » Stacey OUR FRIEND LARRY NEEDS YOUR HELP: BOTH HE AND HIS MOM HAVE MS Nov 24 2006 07:56
3 NEW! » Shell THIS IS WHY I LOVE MySpace...AND MY MySpace FRIENDS - stan Nov 24 2006 11:36
1 NEW! » Mary and Robert Wheelchair bowlers still rolling Nov 18 2006 16:53
1 NEW! » David THIS POST CAME FROM OUR CORRESPONDENT ANNE: A SIMPLE TEST FOR MS Nov 19 2006 10:27
1 NEW! » Darth Woky ™ CLEVELAND CLINIC TIPS ON: STRESS AND MS Nov 20 2006 01:35
3 NEW! » ♥Debbie♥ "FAMOUS PATIENTS AND THE LESSONS THEY TEACH"...THE NEW YORK TIMES Nov 20 2006 05:11
4 NEW! » Tim Foolery Stem cells might cause brain tumors Nov 20 2006 07:22
1 NEW! » WaterDragon {READ THIS!!!-stan} DRUG COMBO SHOWS SHOCKING REVERSAL OF MS SYMPTOMS Nov 21 2006 04:36
1 NEW! » WaterDragon "What if we could actually reverse the damage that MS causes, restoring function..." Nov 21 2006 05:10
1 NEW! » Jeannine Stada said it is no longer to pursue its Interferon-beta project to treat MS Nov 21 2006 07:28
4 NEW! » Shell Clinical Trial Design Nov 22 2006 07:48
4 NEW! » Alpha STUDY FINISHED RE: people's concern about a perceived high rate of MS in Illinois cities Nov 22 2006 11:20
5 NEW! » David New Patent for diagnosing MS Nov 22 2006 13:17
1 NEW! » Roseanne GREAT EXPLANATION OF STEM CELLS AND THEIR POSSIBLE USE IN MS Nov 23 2006 07:37
2 NEW! » Alpha PERSONAL STORY OF THANKSGIVING Nov 23 2006 20:52
3 NEW! » Alpha SOUTH FLORIDA - National MS Health Expo Is November 19th Nov 24 2006 17:06
4 NEW! » Jeannine YOUR COMMENTS HAVE HELPED "FOOL ON THE HILL"...stan Nov 24 2006 19:00
3 NEW! » "Gamma Julie" {first time i've seen a charity benefit solely for low income ms patients-stan} Nov 25 2006 07:08
5 NEW! » Mary and Robert Multiple Sclerosis Society Alert re: funding Nov 25 2006 23:44
3 NEW! » Mary and Robert DACLIZUMAB FOR MS Nov 25 2006 23:46
4 NEW! » queen_racewife GOOD STORY - University of Rochester presses quest for stem cell breakthrough Nov 26 2006 10:50
5 NEW! » Alpha [WOW!!! READ THIS!!-stan] High-tech device helps a martial artist learn how to walk again Nov 26 2006 16:18
2 NEW! » Kendra OUR FRIEND KENDRA NEEDS OUR WISHES OF GOOD LUCK! HER SURGERY IS APPROACHING - stan Nov 27 2006 08:17
5 NEW! » Alpha Results of study on prevalence of MS in Lewistown to be presented Nov 28 2006 08:36
2 NEW! » ♥Debbie♥ "Do you believe in miracles? " By Linda Beck Nov 28 2006 10:02
1 NEW! » ♥Debbie♥ OUR FRIEND AND "STAR COMMENTATOR" KEY HAS GOOD NEWS Nov 28 2006 10:06
3 NEW! » ♥Debbie♥ THIS IS GREAT: FREE BOOKLET FROM THE UK Nov 28 2006 10:14
1 NEW! » ~♥sweet caroline♥~ OUR FRIEND DEBBIE NEEDS A HUG! SHE HAS A MESSAGE FOR EVERYONE Nov 28 2006 21:01
1 NEW! » Francine MS Holiday Gift Guide Nov 29 2006 08:07
8 NEW! » David "Glatiramer acetate therapy for multiple sclerosis" Nov 29 2006 19:30
1 NEW! » David DARTH WOKY: ONE OF MY BEST FRIENDS NEEDS YOUR ADVICE Dec 2 2006 12:38
3 NEW! » ♥Debbie♥ [update-18 comments] JENNIFER NEEDS SUPPORT: "MY LEGS ARE STIFF & LIFELESS" Dec 4 2006 08:14
2 NEW! » Anne SAD STORY FROM TODAYS HEADLINES Dec 5 2006 05:06
4 NEW! » Anne MELISSA NEEDS SUPPORT Dec 5 2006 05:32
2 NEW! » Kendra NO MERCURY RISK IN AMALGAM FILLINGS Dec 5 2006 08:16
2 NEW! » queen_racewife KIDS: "Why are our children's bodies attacking them? Dec 6 2006 02:55
4 NEW! » queen_racewife PERSEVERANCE: GREAT STORY Dec 6 2006 03:07
1 NEW! » queen_racewife HIGH INCIDENCE OF MS IN ILLINOIS TOWN PUZZLES RESEARCHERS Dec 6 2006 03:23
5 NEW! » queen_racewife PERSEVERANCE: GREAT RADIO INTERVIEW Dec 6 2006 03:35
2 NEW! » Shell PERSEVERANCE...Susan Greenop"s personal story Dec 6 2006 04:49
7 NEW! » Alpha STEM CELL STUDY Dec 6 2006 09:32
3 NEW! » (¯`•´¯)Starr(¯`•´¯) ARTISTS FOR MS Dec 6 2006 09:53
8 NEW! » Mich/Neurotrash'd TERI GARR Dec 7 2006 10:18
1 NEW! » Sean GREAT DISCOVERY AT STANFORD MED SCHOOL: Molecule Linked to Autoimmune Disease Relapses Found Dec 8 2006 15:54
2 NEW! » Mary and Robert GIVE CONGRATS TO TIM FOOLERY FOR GETTING A RAISE! Dec 8 2006 19:12
8 NEW! » David Prescription for the Soul Dec 8 2006 21:07
7 NEW! » Alpha GREAT NEW DRUG: Fampridine-SR Dec 9 2006 12:05
7 NEW! » (¯`•´¯)Starr(¯`•´¯) DISABLED STILL FACE OBSTACLES Dec 9 2006 14:31
5 NEW! » Rev UPDATE ON POT IN CANDY BARS FROM YESTERDAY Dec 10 2006 10:57
4 NEW! » ~Ãngël~™ UPDATE: 36 COMMENTS- ADD YOUR STORY & SHARE YOUR ADVICE: MS IS INTERFERING IN ANGEL'S LOVE LIFE Dec 10 2006 11:16
1 NEW! » Wendy SENATE PASSES GREAT NEW BILL FOR MS Dec 11 2006 08:04
5 NEW! » Tim Foolery "Activists are convinced that electrical pollution is making us sick" Dec 11 2006 09:31
6 NEW! » Tim Foolery GREAT STORY OF PERSEVERANCE FROM TODAY'S HEADLINES Dec 11 2006 09:32
1 NEW! » Tim Foolery CONGRATS TO LORA: SHE'S ALMOST DONE WITH LAW SCHOOL Dec 11 2006 09:33
6 NEW! » Tim Foolery A happy fundraising story - stan Dec 11 2006 14:29
2 NEW! » Jenn CONGRATS TO JENN: "I found out last Monday that hubby and I are expecting .2" Dec 11 2006 18:50
7 NEW! » Yvonne UPDATE ON YESTERDAYS TYSABRI STORY: "1000 MS PATIENTS REFUSED TYSABRI: IT COSTS TOO MUCH! Dec 12 2006 06:54
3 NEW! » Renee JILL'S BDAY IS TODAY...PLUS CONGRATS TO HER ON GRAD SCHOOL!! - stan Dec 13 2006 09:43
1 NEW! » WaterDragon 2 IMPORTANT NEW STUDIES ON GRAY MATTER DAMAGE IN MS Dec 14 2006 04:50
6 NEW! » Alpha MS FAMILY BATTLES LYME DISEASE Dec 14 2006 12:14
1 NEW! » Patti (aka Thelma) UPDATE ON MY POST FROM DECEMBER 4TH: "SIF IS GETTING CHEMO TOMORROW" Dec 14 2006 23:18
4 NEW! » Jeannine TYSABRI: RICH WANTS TO TAKE IT ...BUT HAS A QUESTION Dec 15 2006 07:02
5 NEW! » ~Ãngël~™ GREAT STORY ON NEW JERSEY BIKE TEAM Dec 15 2006 09:44
3 NEW! » ~♥sweet caroline♥~ SUPPORT TEAM ALERT: ANGEL HAS HELPED MANY OTHERS-NOW SHE NEEDS OUR SUPPORT - stan Dec 15 2006 16:08
3 NEW! » CARRIE AMAZING NEWS! CONGRATS TO EVERYONE WHO HAS BEEN MAKING COMMENTS! LOOK AT THIS INFO: Dec 15 2006 20:55
7 NEW! » David CONTROVERSIAL CLINIC SHUT DOWN Dec 15 2006 21:40
7 NEW! » Mary and Robert SAD STORY ABOUT JAZZ SINGER Dec 16 2006 14:58
2 NEW! » David "1000 PATIENTS IN THE UK TO BE DENIED TYSABRI: NOT COST EFFECTIVE" Dec 17 2006 12:25
1 NEW! » David BILLY TALLENT: one of my fav bands [my favorite is Hatebreed] - stan Dec 17 2006 13:37
5 NEW! » Jeannine A MESSAGE FROM ONE OF OUR SUPPORT ANGELS: ALPHA...WHO IS STRANDED IN SEATTLE! -stan Dec 18 2006 14:37
4 NEW! » Jeannine TYSABRI FOR CROHN'S DISEASE TOO!!!! Dec 18 2006 14:40
1 NEW! » Jeannine GREAT NEWS ON NEW MS DRUG FOR MS FATIGUE: MCT-125 Dec 18 2006 14:40
5 NEW! » Jeannine GIVE SPHILLY CONGRATS ON GETTING APPROVED FOR A GRANT Dec 18 2006 14:42
6 NEW! » Jeannine "HAPPY NEWS" FROM OUR SUPPORT ANGEL ANNE - stan Dec 18 2006 14:44
2 NEW! » Jeannine SUPPORT GROUP ALERT: I HAVE RECEIVED MANY EMAILS THIS WEEK FROM OUR FRIENDS WHO ARE SAD Dec 18 2006 14:46
3 NEW! » WaterDragon SUPPORT ALERT: "i have been just feeling like why me why did i have to have ms!" - TERI Dec 18 2006 16:57
4 NEW! » SPhilly SUPPORT ALERT: GIVE RainMaker A PAT ON THE BACK FOR STARTING HIS MS TREATMENT - stan Dec 18 2006 22:30
2 NEW! » Darth Woky ™ CONGRATS TO OUR ANGELS OF SUPPORT: YOUR ADVICE HELPED Holy Crip Dec 19 2006 01:32
4 NEW! » <3i data-blogger-escaped--="" data-blogger-escaped-09:57="" data-blogger-escaped-19="" data-blogger-escaped-2006="" data-blogger-escaped-at="" data-blogger-escaped-br="" data-blogger-escaped-coming="" data-blogger-escaped-dec="" data-blogger-escaped-drug="" data-blogger-escaped-glass="" data-blogger-escaped-great="" data-blogger-escaped-looking="" data-blogger-escaped-m="" data-blogger-escaped-new="" data-blogger-escaped-oral="" data-blogger-escaped-soon...hopefully="" data-blogger-escaped-stan="" data-blogger-escaped-the="" data-blogger-escaped-through="" data-blogger-escaped-you="">1 NEW! » (¯`•´¯)Starr(¯`•´¯) 1,039 FRIENDS VISITED OUR BLOG YESTERDAY & READ YOUR 125 COMMENTS!!!!!!!!!!! - stan Dec 19 2006 10:15
4 NEW! » (¯`•´¯)Starr(¯`•´¯) TERI & ALPHA THINK THIS STORY WILL HELP EXPLAIN MS TO YOUR FAMILY: IT'S ALSO ON TYSABRI - stan Dec 19 2006 10:20
1 NEW! » Melissa NEW PAIN DRUG APPROVED FOR MS...IN EUROPE...WHICH MEANS IT WILL HOPEFULLY BE HERE SOON - stan Dec 19 2006 15:10
4 NEW! » Kim SUPPORT ALERT: BOTH SUSAN AND I NEED HELP! - stan Dec 19 2006 19:33
9 NEW! » Jeannine HAPPY HOLIDAY STORY IN TODAY' NEWS -stan Dec 20 2006 09:55
2 NEW! » Jeannine GIVE CHRIS...OUR NEWSEST ANGEL OF SUPPORT A HUG - stan Dec 20 2006 10:05
4 NEW! » Jeannine POSSIBLE NEW MS TREATMENT: SOY!!!!!!!!!!!!!!!! Dec 20 2006 10:27
5 NEW! » Jeannine INTERESTING STUDY ON RURAL VS URBAN USE OF DOCTORS IN MS PATIENTS Dec 20 2006 10:30
4 NEW! » Jeannine DIABETES BREATHROUGH - RELATIONSHIP TO MS? SEE MY POST ABOVE FROM VIVIAN Dec 20 2006 10:34
1 NEW! » Jeannine AN INTERESTING EMAIL ON DIABETES CURE AND I'S RELATION TO MS Dec 20 2006 10:35
7 NEW! » David THIS STORY IS BETTER THAN THE TRASH FICTION BOOKS I LOVE TO READ - stan Dec 20 2006 20:21
6 NEW! » David NEW MS DRUG UPDATE IN THE NEWS: CHR-1103 Dec 20 2006 20:23
4 NEW! » David UPDATE: FDA ADVISORY (WARNING) 2 Rituxan deaths: of Tysabri type..rare brain infection Dec 20 2006 20:30
7 NEW! » There Can Only Be One Me SUPPORT ALERT FOR FRANCINE - SHE HAS HELPED MANY FRIENDS - NOW SHE NEEDS HUGS! - stan Dec 21 2006 06:58
2 NEW! » Jeannine COGNITIVE TRAINING HELPS SENIORS" [STUDY] MAYBE IT WILL HELP MS TOO??? Dec 21 2006 06:59
1 NEW! » Miss Kitty MY MESSAGE TO OUR ANGELS OF SUPPORT- RE: YOUR 2 HOLIDAY GIFTS FROM ME + HELP 4 FRIENDS -stan Dec 21 2006 11:10
7 NEW! » :Vitamin DEE: STORY ON NEW MS DRUG IN THE PIPELINE: NEUROVAX Dec 21 2006 21:31
3 NEW! » queen_racewife READ 42 COMMENTS-MARIES IMPORTANT UPDATE ON HER Dec 22 2006 05:43
2 NEW! » (¯`•´¯)Starr(¯`•´¯) DEBBIE'S CHRISTMAS MESSAGE TO OUR Angels of Support Dec 22 2006 10:03
7 NEW! » (¯`•´¯)Starr(¯`•´¯) GREAT STORY OF A MED STUDENT'S PERSEVERANCE IN TODAYS HEADLINE NEWS - stan Dec 22 2006 10:20
7 NEW! » Anne ANOTHER SUCCESS FOR OUR Angel of Support KELLI'S VIDEO - stan Dec 22 2006 16:55
1 NEW! » Patti (aka Thelma) KISOR...OUR NEWEST ANGEL..HAS A REBIF TIP...ON GIVING YOURSELF A SHOT -stan Dec 22 2006 23:40
6 NEW! » WaterDragon SUPPORT ALERT QUESTION: "what have you heard about mono and ms? - shane Dec 24 2006 07:22
4 NEW! » David A GREAT STORY FROM MED STUDENT SOURCE: "New MS Therapies in Clinical Trials" Dec 24 2006 09:46
7 NEW! » David PERSEVERANCE IN TODAY'S NEWS Dec 24 2006 09:54
6 NEW! » David Romney has said he would end to his political career for his wife, who has MS. Dec 24 2006 10:00
1 NEW! » Luis TYSABRI SUPPORT ALERT: "Please help me Stan!" - JAMIE Dec 25 2006 06:29
4 NEW! » Lisa NEW STUDY ON MS & PREGNANCY Dec 25 2006 12:51
1 NEW! » Chanfb915 High Levels of Vitamin D In the Body May Decrease the Risk of MS: HARVARD PRESS RELEASE Dec 25 2006 18:29
3 NEW! » Mary and Robert ADD YOUR "HAPPY &/or FUNNY STORY" TO THE 31 BELOW: I'M GOING TO PUT THEM IN A SLIDESHOW - stan Dec 27 2006 00:46
1 NEW! » Mary and Robert SUPPORT ALERT UPDATE - 18 COMMENTS: "I am still trying to accept everything (dx Aug 2006)" Dec 27 2006 01:27
2 NEW! » Mary and Robert NEW PHOTOS-CONGRATS TO RENEE: "he popped the big question-he's seen me at my worse with my MS" Dec 27 2006 01:54
2 NEW! » Mary and Robert WELCOME sorormp3: OUR NEWEST Angel...A SUPER Stay-Home Mom and Retired Teacher Dec 27 2006 01:56
2 NEW! » Mary and Robert SUPPORT ALERT: "I'M DEPRESSED: Does anyone know anything about using chemo for MS?" - Valyum Dec 27 2006 01:59
1 NEW! » Mary and Robert OUR 17 YEAR OLD ANGEL ROSE GOT DIAMOND EARRINGS FOR XMAS: NICE BOYFRIEND! - stan Dec 27 2006 02:00
3 NEW! » Mary and Robert "I GOT A JOB OFFER STAN" - YVONNE Dec 27 2006 02:01
5 NEW! » Mary and Robert "a relationship suddenly breaking up. This happened last week-two days before my birthday." Dec 27 2006 02:12
8 NEW! » Mary and Robert "The greatest thing happened to me this past week at work!!!" - PATRICIA Dec 27 2006 02:15
1 NEW! » Mary and Robert "I wonder how I am going to be brave enough to self administer these injections? Dec 27 2006 02:24
4 NEW! » queen_racewife SUPPORT ALERT: "friends & family seem to be "backing off"-not sure how to "deal" with me & MS" Dec 27 2006 03:40
8 NEW! » queen_racewife WELCOME OUR NEWEST SUPPORT ANGEL: AMY Dec 27 2006 03:43
2 NEW! » queen_racewife SUPPORT ALERT: "i pray that i don't have a replapse while with family" - DIERDRE Dec 27 2006 04:03
4 NEW! » queen_racewife GREAT LONG STORY ON MY MAIN MS NEWS SITE - stan [too long 4 this blog] Dec 27 2006 04:05
5 NEW! » queen_racewife LADOSTIGIL (an Alzheimer's drug) for treating MS Dec 27 2006 04:17
3 NEW! » Gypsy Queen GOOD STORY ON EXERCISE FROM TODAY'S NEWS - stan Dec 27 2006 05:34
3 NEW! » Beth NATALIE'S PERSEVERANCE!!! YOUR COMMENTS OF SUPPORT HELPED NATALIE - stan Dec 27 2006 10:44
3 NEW! » David SUPPORT ALERT: "I HAD A MRI..IT SHOWED 1 NEW LESION FOR A TOTAL OF 10" - SUSAN Dec 27 2006 21:23
4 NEW! » David THIS IS A "INDEX OF STORIES" SLIDESHOW THAT IS UNDER CONSTUCTION: CAN U READ THE HEADLINES? Dec 27 2006 21:34
2 NEW! » Anne SUPPORT ALERT: My doctor says I may have MS & Fibromyalgia-does anyone else have both of these? Dec 28 2006 01:09
4 NEW! » HOOLIE 5 NEW TATS TODAY: "TATOOS AGAINST MS" Many have told me tatoos help them deal with MS Dec 28 2006 07:27
4 NEW! » Donna Mojo-"Athos" HAS A MOOD TIP: "I HAVE DAYS WHEN I'M SO LONELY THAT I SIT IN MY ROOM AND CRY" Dec 28 2006 10:25
1 NEW! » "Gamma Julie" SUPPORT ALERT FOR GENEISIS & HER "MS NIGHTS! DO U HAVE THE SAME PROBLEM? TELL US! - stan Dec 28 2006 02:58
1 NEW! » "Gamma Julie" COPAXONE SUPPORT ALERT: JULIE'S HUSBAND IS GETTING LUMPS LIKE A MARBLE @ THE INJECTION SITE!?? Dec 28 2006 03:12
2 NEW! » queen_racewife TYSABRI: HARVARD MED SCHOOL'S TOP 10 STORIES OF 2006 Dec 28 2006 05:28
10 NEW! » ~Ãngël~™ SUPPORT ALERT FOR SANDRA: "I AM SO STRESSED WITH THIS & DON'T KNOW WHAT TO DO" Dec 28 2006 07:49
10 NEW! » Jeannine 1,066 VISITORS & 152 COMMENTS ON OUR BLOG YESTERDAY - stan Dec 28 2006 08:02
6 NEW! » Key MS family's appearance on the ABC television show "Extreme Makeover: Home Edition" Dec 28 2006 12:13
15 NEW! » Katrina (great update: note from Kendra) SUPPORT ALERT: KENDRA NEEDS HUGS AND A NEW DOC!!! -stan Dec 28 2006 12:36
5 NEW! » Yvonne SUPPORT ALERT: "SINCE MY DX MY SEX LIFE HAS BEEN SHIT" DARTH WOKIE Dec 28 2006 12:46
3 NEW! » queen_racewife For kids, MS itself just half the battle: Correctly diagnosing disease can be tricky Dec 28 2006 12:59
15 NEW! » WaterDragon FATIGUE RELIEF: THIS IS ONE OF THE MOST IMPT POSTS I'VE MADE OUT OF 596 I'VE POSTED - stan Dec 28 2006 13:10
4 NEW! » Alpha [4 NEW ANGELS THIS AM] THESE 26 FRIENDS HAVE JOINED OUR 91 ANGELS OF SUPPORT THIS WEEK Dec 28 2006 14:13
16 NEW! » D SUPPORT ALERT FOR OUR NEWEST ANGEL-NANCY WHO HAS "WEIGHT GAIN OF 50 POUNDS" = stan Dec 28 2006 14:19
1 NEW! » Alpha SUPPORT ALERT: CANCER HASN'T STOPPED BRIAN'S WANTING TO BE AN "ANGEL OF SUPPORT" [HUGS! PLEASE]

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Wow! It's no wonder MS is seen as a Cash Cow: THESE MS DRUGS BROUGHT IN THE MOST MONEY LAST YEAR

Teva soaring out in front on a single product and it is no surprise that the Generics pack are waiting in the rear ready for the copaxone patents to expire starting May 2014. However Biogen are backing the most winners with a staggering $5.8 billion worth of business. 
#1 Glaterimer acetate Teva     $4.3 billion
#2 Avonex Biogen Idec           $3.0 billion
#3 Gilenya Novartis                 $1.9 billion
#4 Tysabri Biogen  Idec           $1.7 billion
#5 Betaseron Bayer                 $1.1 billion
#6 Tecfidera Biogen Idec        $0.9 billion
#7 Rebif EMD serono              $0.6 billion
#8 Ampyra Biogen Idec           $0.3 billion
#9 Aubagio Sanofi                   $0.2 billion
#10 Extavia Novartis               $0.2 billion

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Friday

 

85 STORIES & STUDIES HAVE BEEN POSTED IN MARCH'S NEWS SO FAR

  • "It takes about 2 x as long for someone with MS to absorb and process information as someone who does not have MS: Back to School With MS? Here's How"
  • Multiple Sclerosis Treatment Options: Breakdown of Associated Risks
  • Study: Tysabri (Natalizumab) to fingolimod washout in patients at risk of PMLFingolimod, Tysabri
  • Neil Cavuto on Feeling Moved to Tell His Viewers: ‘It’s Not Me, It’s The Multiple Sclerosis’
  • Merck KGaA shores up Rebif defenses to fend off new MS rivalsRebif
  • Play the MS Matching Game: brain games can help exercise your mind
  • Survey showed strong uptake of the new 40-milligram, thrice-weekly version of Teva's Copaxone, estimating that about 40% of MSers will have switched to it after two yearsCopaxone
  • New warning suggested for Ambien...the same sleeping pill that landed a Kennedy before a jury: says patients shouldn't drive for 8 hours after they take meds like Ambien
  • $15 Million awarded to former Newark teacher with MS who says district retaliated against her
  • A Glittering Rock Reunion of 14,300 Fans Becomes the Best of Get-Well Gifts for Guitarist Ronnie Lane
  • Study: 2014 Multiple Sclerosis Therapeutic Update, UCSF MS Department of Neurology, San Francisco, CA
  • Study: High prevalence and no latitude gradient of multiple sclerosis in Norway
  • Study: Supervised exercise training has substantial benefits for MSers, yet 80% of those with MS do not meet recommended levels of moderate-to-vigorous physical activity (MVPA)
  • "British Health Minister Edwin Poots witnessed first-hand how oxygen therapy can help MSers enjoy a better quality of life"
  • Illinois lottery game fund multiple sclerosis research
  • BREAKING NEWS! WARNING: Pfizer Issues Nationwide Recall of Antidepressant Effexor
  • For Runner With M.S., No Pain While Racing, No Feeling at the Finish (New York Times)
  • A MSer's story of how she & her Neuro both had problems with Anthem BlueCross getting her MS treatment refilled:10 BEST
  • Doctors’ #1 Source for Healthcare Information: Wikipedia
  • Merck KGaA shores up Rebif defenses to fend off new MS rivals
  • Novartis, Sanofi, Biogen tout new MS drug researchAubagio, Copaxone, Gilenya, Tysabri
  • My recent struggles made me realize, you only live life one time
  • "Innate Immunotherapeutics delivered results from animal studies which further support its novel MIS416 therapy as a candidate to treat Secondary Progressive Multiple "Sclerosis (SPMS)
  • Oregon Health & Science University today announced the creation of the OHSU Center for Embryonic Cell and Gene Therapy, led by Shoukhrat Mitalipov, Ph.D., a world-renowned leader in embryonic stem cell and gene therapy research
  • Study: Neglecting data from individuals with MS who exhibit head movement during functional magnetic resonance imaging (fMRI) scanning may bias sampling away from individuals with lower cognitive ability
  • Study: MiR-126: a novel route for Tysabri (natalizumab) action?Tysabri
  • "Dr. Monson has developed a validated method for pre-testing people living with MS to determine if they are a carrier of a unique antibody gene that leads to the disease, thus mitigating the long-standing challenge of diagnosis"
  • MS trial to explore vitamin D links
  • Study: Oxygen Cost of Walking in Persons with Multiple Sclerosis: Disability Matters, but Why?
  • A SAD BUT IMPORTANT LESSON FOR ALL MSers: "Inquest hears how MSer dropped match or cigarette onto her bed that engulfed her in flames and burnt down her home
  • This MSer believes marijuana helped put his MS in remission: soon however, Davidson will be forced to destroy the medicine he credits with saving his life
  • Biogen Idec finished 2013 on a high note, with its highly touted oral multiple sclerosis drug Tecfidera producing nearly $400 million in sales during the fourth
  • Study Findings from Biogen Idec, Inc. Provide New Insights into Multiple Sclerosis
  • Slightest change makes myelin come unglued: One common characteristic of diseased myelin is swelling due to MS
  • OMG of the week: Doctors flee homes after declaring strike
  • What Do Healthcare Providers Advise Women with Multiple Sclerosis Regarding Pregnancy?
  • How Inactivity Change MSer's Brains
  • One-liners may hint at feelings about health care
  • RUNNING HELPS ME MANAGE MY MS: Jeanine Parson
  • I'm a mother of 3 young children and here's my horror story of my MS & the new health care law
  • TAKEDA ADMITS TO IMPROPERLY MARKETING BLOCKBUSTER DRUG a AFTER DOCTOR POINTS OUT DATA IN AD DIDNT MATCH RESULTS OF CLINICAL STUDY
  • Study: “Bright spotty lesions” on spinal magnetic resonance imaging differentiate neuromyelitis optica from multiple sclerosis
  • Clues To Causes Of Nerve Cell Degeneration in MS Provided By Spasticity Gene Finding
  • Minn. physicians ponder medical pot: Is marijuana an effective treatment for pain, illness and disease?
  • Study: MRI evaluation of grey matter atrophy and disease course in multiple sclerosis: an overview of current knowledge
  • Variables associated with patient activation in persons with multiple sclerosis
  • What Vitamin D Dosage Do I need? How Much Sun Do I Need?
  • Optical coherence tomography and visual evoked potentials: which is more sensitive in multiple sclerosis?
  • Express Scripts stops covering older, commonly used treatments such as Bayer's multiple sclerosis drug Betaseron on clinical, cost-effectiveness grounds
  • Study: Antiviral drug Ganciclovir Inhibits Neuroinflammation in Mouse Model of MS
  • Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis
  • Study: Constraint-induced movement therapy increased neuroplasticity in MS patients according to MRI findings, whereas massage, yoga, and other "complementary/alternative medicine" treatments did not.
  • Arshiya’s special talent: I used to jump all the way down the steps in Hodge Lee in one leap. I felt like Superman, or rather, Superwoman. That was before I got MS
  • TEVA'S COPAXONE PATENT IS UP AND ITS DESPERATE TO KEEP PATIENTS & INSURERS
  • DOES THIS NEW STUDY MEAN ANYTHING FOR MS PATIENTS?: "Medical Marijuana: Studies Find No Benefit for RA: Rheumatologists should not currently be recommending the use of medical marijuana to their patients for relief of chronic pain, researchers stated
  • 4 Things All Doctors Need To Know About Health IT Security
  • Video: THE SCANDAL THAT ROCKED THE PATIENT SAFETY MOVEMENT BREAK...
  • CAN CAFFEINE HELP AN MSers MEMORY: Caffeine’s little memory jolt garners a lot of excitement
  • Air Force Academy's future rests in Lt. Gen. Michelle Johnson steady hands: the institution's first female superintendent, has been tearing down barriers all her life including MS
  • Senate Passes Casey MS Resolution Ahead of Multiple Sclerosis Awareness Week
  • "MS doesn't define us - it's just there"
  • 7 women are suing Doctor & health network for medical negligence, claiming the doctor misdiagnosed them with multiple sclerosis
  • "My 1st experience as an immunologist diagnosed with MS" by Griselda Zuccarino-Catina, PH.D.
  • DOCTORS BEDSIDE MANNER: written by a doctor
  • Immunophenotyping Separates MS Subtypes by Neuroinflammation
  • What's new in the fight against MS? USA Today
  • Another big beast joins the MS Drug fray: ofatumumab phase 2 trial results
  • MSnewsChanel.com.com
  • Study may provide future insights into causes and mechanisms of MS
  • 30% of the 16,651 people who died of an opioid overdose also had taken a benzodiazepine
  • Working as a full time police officer & living with MS
  • Here's 5 ways to help ease the pain of winter months
  • Obamacare Hikes Cost to Patients of Specialty Drugs for MS
  • The battle of a 6th grader recently diagnosed with MS
  • Study: Stethoscopes carry more bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA), than a physician’s hand
  • Merck's Rebif is a 3rd major MS drug to be discovered in Israel: The Israeli Connection
  • Kristen discovers running as way to combat her MS
  • Cara Therapeutics has exciting new MS drugs in their pipeline
  • Study: See One, Do One: Watching Action Boosts Brain Volume, Ability
  • Study: Graph theoretical analysis indicates cognitive impairment in MS stems from neural disconnection
  • We've posted 314 Studies & Stories for you so far this week
  • FOR DOCTORS ONLY: 15 Smartphone Apps to Improve Your PracticeDocs Only
  • WEEKEND LOL REPORT: Medical School Limiting the Number of Creepy Applicants to Cut Down on Creepy Doctors
  • Video: 'Dallas Buyers Club' connects with MSers
  • FOR DOCTORS ONLY: Study Companion: Mastering Clinical Concepts in MS Management

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Correcting vitamin D deficiency early in Betaseron (interferon beta-1b) treatment may reduce MS disease activity

 

Pharmacy Choice - Pharmaceutical Bayer Introduces First Bluetooth-enabled Injection Management System for Multiple Sclerosis Patients on Betaseron

 

IMPORTANT UPDATE: "American specialists should also be aware of this worrisome but rare adverse effect, said MS expert Aaron Miller, MD, Icahn Mount Sinai School of Medicine, NYC"

Aaron Miller, MD,
Icahn Mount Sinai School of Medicine
New York City
Cases of unexpected, serious, and even fatal thrombotic microangiopathy (TMA) linked to use of a new serum-free formulation of interferon beta (Rebif) have emerged in patients with MS
In a Letter to the Editor published in the March 27 issue of the New England Journal of Medicine, David Hunt, PhD, from Edinburgh University, and colleagues reported on 4 such cases that were diagnosed in South Scotland during an 18-month period. Regulatory authorities in the United Kingdom received 6 additional spontaneous reports of disorders related to TMA and the same formulation of interferon beta, which was introduced in Europe in September 2007, the letter notes. 

The authors call for specialists to be on the lookout for signals of this rare adverse effect of interferon beta in their patients with MS.

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Study: Long-term impact of interferon beta-1b in patients with CIS: 8-year follow-up of BENEFIT

 

Cambridge Consultants & Novartis introduce new device 'ExtaviPro 30G auto-injector' for MS patients

 

Multiple Sclerosis and Pregnancy: Current Considerations

 

HOW MS MEDICATIONS DIFFER FROM EACH OTHER

 

Tecfidera Captures the Largest U.S. Neurologist-Reported Patient Share Among Oral Disease-Modifying Multiple Sclerosis Therapies Ten Months Post-Launch

 

Paleo Diet & Functional Medicine Helps Doctor Fight Progressive MS

I am a professor of medicine at the University of Iowa and for most of my career, I believed wholeheartedly in the power of modern medicine, in our latest greatest drugs, in our ever more expert procedural interventions. For many years, I focused on treating disease, not on creating health, because that is what I was taught to do. I didn’t know any better, but I was certainly not a “physician of the future.”
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Synthetic Biologics Announces Issuance of U.S. Patent patents for MS and other autoimmune diseases covering the uses of its oral estriol candidate, Trimesta

 

Express Scripts stops covering older, commonly used treatments such as Bayer's multiple sclerosis drug Betaseron on clinical, cost-effectiveness grounds

 

7 women are suing Doctor & health network for medical negligence, claiming the doctor misdiagnosed them with multiple sclerosis

 

Vitamin D Levels Appear to Be Robust Predictor of MS Progression

 

FREE MS RESEARCH UPDATE: a comprehensive overview of research findings on all of the FDA-approved disease-modifying therapies, as well as many experimental treatments



This year's expanded MS Research Update incorporates new information about the approved disease-modifying therapies (DMTs), as well as numerous experimental drugs currently under investigation for the long-term treatment of multiple sclerosis (MS). Highlights and recent research results are provided for each drug. Please note that symptom-management drugs are not included in this report.

DOWNLOAD YOUR FREE PDF OR ORDER A FREE COPY
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15 STUDIES IN FRIDAY'S NEWS

 PLUS: 1590 new Studies we posted from 11/1 to Thursday 2/12 Start at the Bottom!


The NBSS, developed specifically to assess the symptoms and consequences associated with neurogenic bladder dysfunction, has appropriate psychometric properties. Depending on the measurement need, individual domains may be selected, or it can be used as a comprehensive score.

The fraction of intrathecally-produced VZV-specific IgG of the total intrathecally produced IgG discriminates between patients with VZV reactivation and MS. Our results provide further evidence that intrathecally-produced VZV antibodies are part of the polyspecific immune response in patients with MS.

 In addition to autoantigens implicated in thyroid autoimmunity, fibrocytes and derivative fibroblasts express multiple autoantigens associated with T1DM. This expression results from active gene promoters and abundant steady-state mRNA encoding ICA69 and IA-2. These latest findings demonstrate that fibrocytes express antigens relevant to multiple forms of endocrine autoimmunity. They suggest the potential for these cells playing a direct role in immune reactivity directed at the thyroid and pancreatic islets.

MMPs can also enhance the cleavage of myelin basic protein (MBP) and the demyelination process. Regarding the growing data on the roles of MMPs and their tissue inhibitors (TIMPs) in the pathogenesis of MS, this review discusses the role of different types of MMPs, including MMP-2, -3, -7, -9, -12 and -25, in the immunopathogenesis and treatment of MS.

In a real-world setting, patients with MS who switched from IFNs to fingolimod were significantly less likely to experience relapses than those who switched to GA.
Read Study Pubmed.gov



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15 STUDIES IN THURSDAY'S NEWS

 PLUS: 1575 new Studies we posted from 11/1 to Wednesday 2/12 Start at the Bottom!




In patients with SSc, serum levels of ICAM-1 and P-selectin may serve as prognostic indicators of respiratory dysfunction and physical disability, respectively. Further longitudinal studies of larger populations are needed to confirm these findings.

Seizures can occur at any stage during the course of MS, but it is more common during the early stages.

In a real-world setting, patients with MS who switched from IFNs to fingolimod were significantly less likely to experience relapses than those who switched to GA.

In the NARCOMS cohort, functional health literacy is high. However, lower levels of health literacy are associated with adverse health behaviors and greater health care utilization.
Read Study at Pubmed.gov

In the pathogenesis of MS, this review discusses the role of different types of MMPs, including MMP-2, -3, -7, -9, -12 and -25, in the immunopathogenesis and treatment of MS.
Read Study at Pubmed.gov

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15 STUDIES IN WEDNESDAY'S NEWS

 PLUS: 1560 new Studies we posted from 11/1 to Tuesday 2/11 Start at the Bottom!



Seminal data regarding its use in MS, the known mechanism(s) of action, and contemporary studies focusing on efficacy and safety data will be reviewed. The role of chemotherapeutic agents in the management of MS and implications for therapeutic intervention are also discussed. 
Read Study at Pubmed.gov

The best current evidence for the efficacy of glucocorticoid treatment in MS, by far, comes from the optic neuritis treatment trial, which used high-dose intravenous methylprednisolone for the first 3 days followed by an 11-day course of low-dose oral prednisone. 
Read Study at Pubmed.gov

It is hoped that, through an understanding of the earliest aspects of the MS disease process, critical insights will be gained about the genesis of MS. 
Read Study at Pubmed.gov

Major technical improvements in MRI hardware and pulse sequence design allow more specific and potentially more sensitive treatment metrics required for targeting outcomes most relevant to neuronal degeneration, remyelination and repair. 
Read Study at Pubmed.gov

This chapter reviews the current evidence, taken from both clinical and paraclinical sources, as it relates to establishing this prognosis and provides insight to where, in the future, we need to look. 
Read Study at Pubmed.gov

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15 STUDIES IN TUESDAY'S NEWS

 PLUS: 1545 new Studies we posted from 11/1 to Monday 2/10 Start at the Bottom!



These findings support previous systematic reviews, however publication bias cannot be excluded. The methodological conduct of studies could be improved, particularly with regard to reporting and conduct of laboratory analyses.
Read Study at Pubmed.gov

Despite the long follow-up, the risk of MS appears lower in New South Wales children compared to previously reported cohorts. Radiological features are more predictive than clinical features in predicting MS. The McDonald 2010 criteria performed well although the dissemination in time criteria on baseline scans is difficult to apply to children with encephalopathy.
Read study at Pubmed.gov

Our findings suggest that higher CR in individuals with MS may mediate between cognitive performance and brain pathology. CR-related compensation may, however, fail with progression of damage. The time window of opportunity for therapeutic approaches aimed at intellectual enhancement most likely lies in the earliest disease stages.
Read Study at Pubmed.gov

Further evidence of vitamin D deficiency as a causal factor, its molecular targets in MS and its prospect as a therapeutic and preventative agent are questions that warrant further study.
Read Study at Pubmed.gov

Patients with ≥2 relapses annually have higher resource utilization and costs. The difference in cost was over twice as large in treatment-naïve patients versus treatment-experienced patients. HRA was also associated with an increased likelihood of starting DMT treatment (treatment-naïve patients), and switching or discontinuing DMT therapy (treatment-experienced patients).
Read Study at Pubmed.gov 

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15 STUDIES IN MONDAY'S NEWS

 PLUS: 1530 new Studies we posted from 11/1 to Sunday 2/9 Start at the Bottom!

Farming and exposure to livestock may be important factors in the development of FCD among women, with this finding further revealed after the confounding effect of parity or number of children is considered.
Read Study at Pubmed.gov

Results suggest that demyelinated lesions in MS mainly have a remote effect on the thalamus and that the measurement of CBF using ASL could be an objective marker for monitoring disease activity in MS.
Read Study at Pubmed.gov

Here, we summarize currently accepted therapeutic principles and the drugs in late stages of development, as well as spotlighting potential novel openings for future research.
Read Study at Pubmed.gov

Collaboration between neurologists and psychiatrists whilst caring for patients displaying neuropsychiatric manifestations of MS is crucial to enable more accurate diagnoses and try to improve treatment and overall prognosis. 
Read Study at Pubmed.gov

In summary, in this retrospective analysis, daclizumab therapy substantially decreased the rate of brain atrophy in relapsing-remitting MS in comparison to other disease-modifying therapies, predominantly interferon β.
Read Study at Pubmed.gov

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15 STUDIES IN SUNDAY'S NEWS

 PLUS: 1515 new Studies we posted from 11/1 to Saturday 2/8 Start at the Bottom!


In this paper we present a new unsupervised approach addressing this problem with dictionary learning and sparse coding methods. We show its general applicability to the problem of lesion segmentation by evaluating our approach on synthetic and clinical image data and comparing it to state-of-the-art methods.
Read Study at Pubmed.gov

In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.
Read Study at Pubmed.gov

Long walking tests and patient-reported MSWS-12 were more appropriate than short walking tests in detecting clinically meaningful improvement after physical rehabilitation, particularly the MSWS-12 for moderate to severely disabled pwMS.
Read Study at Pubmed.gov

The use of patient self-assessed outcome measures that appraise the quality of diagnosis communication is also important to allow health services to understand and meet the needs and preferences of PwMS.
Read Study at Pubmed.gov

Quantitative gait assessment reveals subtle gait disorders in patients with low disability of relapsing-remitting multiple sclerosis. The impact of different cognitive domains on gait induces specific gait disturbances that highlight the strong interaction between gait and cognition.
Read Study at Pubmed.gov

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15 STUDIES IN SATURDAY'S NEWS

 PLUS: 1500 new Studies we posted from 11/1 to Friday 2/7 Start at the Bottom!


Studies are needed to further clarify why suicide ideation and suicidal behavior are associated with neurological diseases, in order to improve quality of life, alleviate patient distress, and prevent nonfatal and fatal suicide attempts in veteran and non-veteran populations.
Read Study at Pubmed.gov

Obesity in childhood or adolescence is associated with an increased risk of pediatric-onset and adult-onset multiple sclerosis
Read Study at Pubmed.gov

Autoimmune disorders are rare, but some of them tend to occur together with MS at a higher rate than in controls. Although women are generally more prone to ADs than men, significantly increased occurrence of other ADs were only found in male MS patients.
Read Study at Pubmed.gov

Paternal MS and MS-related clinical factors were not significantly associated with birth outcomes (p>0.05). This study provides assurance to expecting fathers with MS and their families.
Read Study at Pubmed.gov

This study showed that PET imaging of demyelination and remyelination processes in focal lesions is feasible.
Read Study at Pubmed.gov

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15 STUDIES IN FRIDAY'S NEWS

 PLUS: 1485 new Studies we posted from 11/1 to Thursday 2/6 Start at the Bottom!

A study was done to assess the cost-effectiveness of the Disease Modifying Treatments (DMT), Glatiramer Acetate (GA) and Interferon beta-1a (IFN) in monotherapy alone and in combination for the prevention of relapses among Spanish patients aged between 18 and 60 years old with established Relapsing-Remitting Multiple Scerosis (RRMS).
Read Study at Pubmed.gov

Article reviews the current understanding of the interactions between multiple sclerosis (MS) and pregnancy, and implications for reproductive counseling. This is a key topic in MS because the typical patient is a young woman of childbearing age.Pregnancy has a profound effect on MS disease activity. Identification of the responsible mechanisms for this effect should lead to new disease insights and therapeutic strategies. 
Read Study at Pubmed.gov

Pain-related mood influences pain perception differently in fibromyalgia and multiple sclerosis.
Read Study at Pubmed.gov

Gait disorders need to be identified and managed early in the course of MS, using a multimodal approach that needs to be adjusted over time based on the results of periodic assessments.
Read Study at Pubmed.gov

Fatigue needs to be recognized as an important condition that is not only a symptom but may also be quantified and can be modified by various measures depending on the underlying cause.
Read Study at Pubmed.gov

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15 STUDIES IN THURSDAY'S NEWS

PLUS: 1470 new Studies we posted from 11/1 to Wendnesday 2/5 Start at the Bottom! 



Current guidelines have recognized the benefits of early treatment of MS with DMTs. However, there are a number of barriers to implementing early MS treatment. Early diagnosis and treatment of MS can be hindered because patients may delay consulting a physician about their neurological symptoms or may be reluctant to start DMT. Read study at National Institute of Health

Due to the current lack of appropriate clinical guidance and insufficient head-to-head data on disease-modifying drugs, strategies for health plans and clinical management have been designed using the best available evidence. Undoubtedly, management of this class will continue to evolve with the launch of newer agents.
Read study at National Center for Biotechnology Information


A period of diagnostic uncertainty regarding the transition from RRMS to SPMS existed in many of our patients. Potential reasons included the subtle nature of early progressive disease and caution in applying a progressive label, in light of the lack of evidence-based treatments as well as third-party payer concerns. Delay in definitive identification of an SPMS phenotype has a variety of implications related to patient care and research.
Read study at National Center for Biotecnology Information

This study supports the concept that modifications of the tear proteome can reflect biological abnormalities associated with multiple sclerosis and perhaps other inflammatory conditions affecting the CNS. In addition, alpha-1-antichymotrypsin elevation in tear fluid emerges as a promising biomarker for the diagnosis of multiple sclerosis.

The present study examined the functioning of explicit and implicit memory in MS. Results showed that implicit memory was not significantly impaired in the MS subjects, and that they were impaired on recall but not recognition. A correlation was found between implicit memory performance and disability status in MS patients. 


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15 STUDIES IN WEDNESDAY'S NEWS

 

15 STUDIES IN TUESDAY'S NEWS

PLUS: 1440 new Studies we posted from 11/1 to Monday 2/2 Start at the Bottom! 



Magnetic susceptibility of MS lesions increased rapidly as it changed from enhanced to nonenhanced, it attained a high susceptibility value relative to NAWM during its initial few years (approximately 4 years), and it gradually dissipated back to susceptibility similar to that of NAWM as it aged, which may provide new insight into pathophysiologic features of MS lesions.

In a cohort with different stages of MS, higher EA attenuated the negative effects of white matter lesion burden and third ventricle width (suggestive of thalamic atrophy) on cognitive performance. Actively enhancing cognitive reserve might thus be a means to reduce or prevent cognitive problems in MS in parallel to disease modifying drugs.

These data suggest that retrograde (trans-synaptic) axonal degeneration stops at the inner nuclear layer, a neuronal network capable of plasticity. In contrast, there seems to be no neuroplasticity of the primary visual cortex, rendering the structure vulnerable to anterograde (trans-synaptic) degeneration.

Simultaneous characterizations of changes in tonic and phasic reflexes and nonreflex changes in joint elastic stiffness and viscosity in neurological disorders may help us gain insight into mechanisms underlying spasticity and develop impairment-specific treatment.

Very rapid functional changes in the excitability of cortical circuits involved in motor control can be induced by steroids, before any process of remyelination or axonal regeneration has time to occur. The net effect of steroids on the balance between intracortical GABAergic inhibition and glutamatergic facilitation was in favour of weaker inhibition or stronger facilitation, which could lead to improving the motor performance in MS patients.

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15 STUDIES IN MONDAY'S NEWS

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The majority of Italian neurologists participating in our study have a good perception of their ability to manage this difficult communicating process and believe in the great effect this moment may have on a life-long disease experience. Improving communication skills may help the therapeutic alliance, enhancing patients' acceptance of the disease, as well as motivation and adherence to treatment.

It is possible that, with further such supportive data, international guidelines on MS treatment in young women who intend to get pregnant may need to be revised.

A significant interaction between Alerting and Executive Control was also found in the MS patients (p = .007). Early relapsing-remitting multiple sclerosis particularly affects the Alerting domain of attention, whereas the Orienting and Executive Control domains are not affected.

The GM is atrophic in MS. Although lower WM volume is associated with greater disability, as might be expected, WM volume was on average in the normal range. This paradoxical result might be explained by the presence of coexisting pathological processes, such as tissue damage and repair, that cause both atrophy and hypertrophy and that underlie the observed disability.

ApEn results revealed that the natural fluctuations present during gait in the stride length and step width time series are more regular and repeatable in patients with MS. These changes implied that patients with MS may exhibit reduced capacity to adapt and respond to perturbations during gait.


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15 STUDIES IN SUNDAY'S NEWS

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In this small, uncontrolled pilot study, there was a significant improvement in fatigue in those who completed the study. Given the small sample size and completer rate, further evaluation of this multimodal therapy is warranted.

These data suggest that retrograde (trans-synaptic) axonal degeneration stops at the inner nuclear layer, a neuronal network capable of plasticity. In contrast, there seems to be no neuroplasticity of the primary visual cortex, rendering the structure vulnerable to anterograde (trans-synaptic) degeneration.

The number of patients becoming pregnant during fingolimod therapy remains small and does not permit firm conclusions to be drawn about fetal safety of fingolimod in humans. Given the known risks of teratogenicity in animals and the present data, women of childbearing potential should use effective contraception during fingolimod therapy and for 2 months after discontinuation.

The relapse rate in children with multiple sclerosis is higher than in adult-onset disease. Following acute treatment, recovery after the first attacks is usually excellent, but patients with childhood-onset multiple sclerosis reach permanent disability or enter the secondary progressive disease course 10 years younger than patients with adult-onset multiple sclerosis.

Currently, various pharmacological agents such as antiepielptics, non-steroidal anti-inflammatory agents, and even corticosteroids are used to suppress various painful conditions associated with MS. Non-pharmacological procedures such as massage therapy have also been used in the treatment of MS patients. The authors present a review of recent findings in pathophysiology and management of pain in MS patients.

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15 STUDIES IN FRIDAY'S NEWS

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Magnetic susceptibility of MS lesions increased rapidly as it changed from enhanced to nonenhanced, it attained a high susceptibility value relative to NAWM during its initial few years (approximately 4 years), and it gradually dissipated back to susceptibility similar to that of NAWM as it aged, which may provide new insight into pathophysiologic features of MS lesions.

In a cohort with different stages of MS, higher EA attenuated the negative effects of white matter lesion burden and third ventricle width (suggestive of thalamic atrophy) on cognitive performance. Actively enhancing cognitive reserve might thus be a means to reduce or prevent cognitive problems in MS in parallel to disease modifying drugs.

Grey matter damage - global and regional - has the potential to become a marker of disease activity, complementary to the currently used magnetic resonance markers (global brain atrophy and T2 hyperintense lesions). Furthermore, it may improve the prediction of the future disease course and response to therapy in individual patients and may also become a reliable additional surrogate marker of treatment effect.

results confirm the important role of the immune system and specifically B cells in MS and suggest that MS risk variants exert a gene regulatory role. Previous studies assessing MS risk variants in T cells may be missing important effects in B cells. Similar analyses in other immunological cell types relevant to MS and functional studies are necessary to fully elucidate how genes contribute to MS pathogenesis.

Fatigue management program outcomes for people with MS are moderated by age, gender, and impairment.
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15 STUDIES IN THURSDAY'S NEWS

PLUS: 1365 new Studies we posted from 11/1 to Wednesday 1/29 Start at the Bottom! 


Employment status was an explanatory variable for physical health and mental health in the younger patients. EDSS played a significant role in physical health for all patients. A vocational rehabilitation program could prevent eventual nonemployment and improve health outcomes in older MS people.

Simultaneous characterizations of changes in tonic and, phasic reflexes and nonreflex changes in joint elastic stiffness and, viscosity in neurological disorders may help us gain insight into, mechanisms underlying spasticity and develop impairment-specific, treatment.

Using an active prospective surveillance system and the McDonald criteria for first MS diagnosis the age-related incidence of pediatric MS in Germany was uncovered and is more common than in previous estimates. Thorough application of McDonald criteria and inclusion of spinal MRI data allowed for early diagnosis in almost 90% of cases.

A high prevalence of urinary symptoms and urodynamic dysfunctions in patients with CISs and an association of urinary symptoms with quality of life measures were found. These results highlight the importance of identifying and optimally treating urinary symptoms also at the very early stages of MS.

The inflammatory mechanisms associated with lesion formation in MS are to a large extent reflected in experimental models of inflammatory demyelination, such as autoimmune encephalomyelitis. This is not the case for the amplification mechanisms of oxidative injury, which mainly operate in the progressive stage of the disease. GLIA 2014.
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New research shows that Multiple Sclerosis may steal as much as six years from patients' lifespans.

New research shows that Multiple Sclerosis may steal as much as six years from patients' lifespans.
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15 STUDIES IN WEDNESDAY'S NEWS

 

15 STUDIES IN TUESDAY'S NEWS

 

Dr. Alberto Ascherio, a professor of epidemiology and nutrition at the Harvard School of Public Health and lead author, said that the sunshine vitamin can prove beneficial to early stage MS patients.

Dr. Alberto Ascherio
Dr. Alberto Ascherio, a professor of epidemiology and nutrition at the Harvard School of Public Health and lead author, said that the sunshine vitamin can prove beneficial to early stage MS patients.
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15 STUDIES IN MONDAY'S NEWS