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Timothy L. Vollmer, MD
Department of Neurology
University of Colorado Health Sciences Center Professor

Co-Director of the RMMSC at Anschutz Medical Center

Medical Director-Rocky Mountain MS Center
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Brian R. Apatoff, MD, PhD
Multiple Sclerosis Institute
Center for Neurological Disorders

Associate Professor Neurology and Neuroscience,

Weill Medical College of Cornell University

Clinical Attending in Neurology,
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Medicine Damaged My
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I've Had 47 Surgeries
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The Monster is Attacking
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How To Reduce The Side
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Before MS, I spent
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I checked in to the
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My Neuro Wants
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This Is My 1st Column, It's About Being In A Trial For Alemtuzumab (Campath)
This Pill Got Rid of
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My Relationship With
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By 4 Weeks I Gained
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1 Year Ago My
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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
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Friday

 

Vitamin D Levels Appear to Be Robust Predictor of MS Progression

Higher vitamin D levels in persons with multiple sclerosis (MS) were associated with a lower degree of MS activity, magnetic resonance imaging lesion load, brain atrophy, and disease progression during 5 years of follow-up in the Betaferon/Betaseron in Newly Emerging Multiple Sclerosis for Initial Treatment (BENEFIT) trial (Ascherio A et al. JAMA Neurol. doi:10.1001/jamaneurol.2013.5993 [published online January 20, 2014]).
Some 465 patients with clinically isolated syndrome (their first neurological episode, caused by inflammation or demyelination of nerve tissue) were randomized to early vs late treatment with interferon beta-1b (IFNB-1b). Compared with those who had 25-hydroxyvitamin D serum concentrations less than 50 nmol/L in the first 12 months following their first neurological episode, those with serum levels of 50 nmol/L or greater had a significantly lower rate of new active lesions and relapse, a significantly lower yearly increase in T2 lesion volume, and lower disability during the following 4 years.
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